Thermo Fisher Scientific S100A10 Recombinant Rabbit Monoclonal Antibody (ARC0720)
S100A10 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot, IHC, ELISA에 적합합니다. HEK293 세포에서 발현되었으며, 고순도의 친화 크로마토그래피 정제 제품입니다. 인체 시료 연구용으로 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0720 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–97 of human S100A10 (P60903) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.23 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849085 |
Product Specific Information
Immunogen sequence:
MPSQMEHAME TMMFTFHKFA GDKGYLTKED LRVLMEKEFP GFLENQKDPL AVDKIMKDLD QCRDGKVGFQ SFFSLIAGLT IACNDYFVVH MKQKGKK
Target Information
The S-100 family of calcium-activated proteins interacts with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, forming a heterotetrameric complex with Annexin II. This association is not required for plasma membrane localization or plasminogen activation. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B virus polymerase, facilitating its partial nuclear localization and suggesting a role in viral replication.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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