Thermo Fisher Scientific FANCB Monoclonal Antibody (2B10)
FANCB 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse IgG2a 단일클론 항체. Western blot과 ELISA에 적합하며, PBS 완충액에 보존제 없이 액상 형태로 제공. Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B10 |
| Immunogen | FANCB (NP_689846.1, 750–858 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GSENFLIDNM AFTLEKELVT LSSLSSAIAK HESNFMQRCE VSKGKSSVVA AALSDRRENI HPYRKELQRE KKKMLQTNLK VSGALYREIT LKVAEVQLKS DFAAQKLSN
Target Information
The Fanconi anemia complementation group (FANC) includes FANCA, FANCB, FANCC, FANCD1 (BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (BRIP1), FANCL, FANCM, and FANCN (PALB2).
Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.
These proteins form a common nuclear complex despite lacking sequence similarity. FANCB encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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