Thermo Fisher Scientific FIP1L1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

4-8 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the C-terminal of human FIP1L1 (aa 509-558). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FIP1L1,uniProtId:Q6UN15-1,ncbiNodeId:9606,antigenRange:509-558,antigenLength:594,antigenImageFileName:PA5-41914_FIP1L1_Q6UN15-1_Rabbit.svg,antigenImageFileNamePDP:PA5-41914_FIP1L1_Q6UN15-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2607209

Product Specific Information

Peptide sequence: EYAERGYERH RASREKEERH RERRHREKEE TRHKSSRSNS RRRHESEEGD

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%

Target Information

FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3`-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.