Thermo Fisher Scientific NIPA4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NIPA4. Recombinant protein control fragment (Product #RP-96939).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644687

Product Specific Information

Immunogen sequence: FKDLDISCAS LPHMHKNPPP SPAPEPTVIR LEDKNVLVDN IELASTSSPE EKPKVFIIHS

Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 82%.

Target Information

NIPAL4 acts as a Mg(2+) transporter and can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+). NIPAL4 may also be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway. The NIPAL4 gene likely encodes a membrane receptor. Mutations in the NIPAL4 gene have been associated with autosomal recessive congenital ichthyosis. Diseases associated with NIPAL4 include Ichthyosis, Congenital, Autosomal Recessive 6 and Autosomal Recessive Congenital Ichthyosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.