Thermo Fisher Scientific NIPA4 Polyclonal Antibody

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50 dilution tested

Product Specifications

Product Specific Information

• Immunogen sequence: FKDLDISCAS LPHMHKNPPP SPAPEPTVIR LEDKNVLVDN IELASTSSPE EKPKVFIIHS
• Antigen sequence identity: Mouse – 78%, Rat – 82%

Target Information

NIPAL4 acts as a Mg(2+) transporter and can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+), and Co(2+), though to a lesser extent than Mg(2+).
NIPAL4 may function as a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway. The NIPAL4 gene likely encodes a membrane receptor.
Mutations in NIPAL4 are associated with autosomal recessive congenital ichthyosis (ARCI6) and related skin disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.