Thermo Fisher Scientific IL12RB1 Polyclonal Antibody
IL12RB1 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot 등에 사용 가능. 합성 펩타이드 항원으로 제작되었으며, 인체 반응성을 가짐. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (HVSVKNHSLDSVS) corresponding to the internal amino acids of IL12RB1 (aa 451–464) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983467 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily.
It binds to interleukin 12 with low affinity and forms part of the IL12 receptor complex.
This protein forms a disulfide-linked oligomer required for IL12 binding activity.
Coexpression with IL12RB2 leads to formation of high-affinity IL12 binding sites and reconstitution of IL12-dependent signaling.
Lack of expression results in immunodeficiency in patients with severe mycobacterial and Salmonella infections.
Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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