Thermo Fisher Scientific CK1 alpha Monoclonal Antibody (3C10F7, 3C10G5, PMC01, 4D12B3,3C10F7C11)
CK1 alpha 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단일클론 항체로, WB, IHC, ELISA 등 다양한 연구용 분석에 적합. 인간 시료에 반응하며 비결합형 액상 형태로 제공. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C10F7, 3C10G5, PMC01, 4D12B3, 3C10F7C11 |
| Immunogen | Purified recombinant fragment of CK1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10986335 |
Product Specific Information
MA5-15300 targets CK1 in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The MA5-15300 immunogen is a purified recombinant fragment of CK1 expressed in E. coli.
Target Information
CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, which encodes serine/threonine kinases that preferentially phosphorylate acidic substrates.
CKI proteins are monomeric (25–55 kDa) and are found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells.
They phosphorylate a large number of proteins and participate in Wnt signaling.
CK1 alpha phosphorylates CTNNB1 at Ser-45 and may phosphorylate PER1 and PER2.
It may also play a role in chromosome segregation during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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