Thermo Fisher Scientific EAR2 Polyclonal Antibody
Thermo Fisher Scientific의 EAR2 Polyclonal Antibody는 Rabbit에서 유래한 IgG 항체로, Human, Mouse, Dog 등 다양한 종에 반응합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 단백질 발현 연구 및 전사 조절 연구에 활용됩니다.
- 카탈로그번호
- PA523321
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acids 20–70 of human NR2F6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540845 |
Target Information
Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements containing imperfect 5'-AGGTCA-3' repeats recognized by other nuclear hormone receptors. Modulates hormonal responses and represses transcriptional activity of several genes including LHCGR, REN, and OXT. Inhibits thyroid hormone receptor (THRB) binding to TREs, affecting triiodothyronine-dependent transcription. Also inhibits NFATC DNA binding, represses IL-17 expression in Th-17 cells, and may play a role in immune tolerance and autoimmunity. Involved in forebrain circadian clock development and locus coeruleus formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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