Thermo Fisher Scientific PTX3 Recombinant Rabbit Monoclonal Antibody (10D9)
인간 PTX3 단백질을 인식하는 재조합 토끼 단클론 항체로, Flow Cytometry와 ELISA에 사용 가능. HEK293 세포에서 발현되며, 비결합형 액상 형태로 제공. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 보장. 연구용으로만 사용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:50–1:200
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10D9 |
| Immunogen | A synthesized peptide derived from human PTX3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092574 |
Target Information
Pentraxins are a protein superfamily characterized by a cyclic multimeric structure. PTX3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that plays a non-redundant role in resistance to selected microbial agents. PTX3 belongs to the family of long pentraxins, which have C-terminal pentraxin domains and novel amino-terminal domains. It binds selected pathogens including Aspergillus fumigatus, Pseudomonas aeruginosa, and Salmonella typhimurium. PTX3 is synthesized in IgA glomerulonephritis, activates mesangial cells, and its secretion in adipose cells can be induced by TNF. It is involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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