Thermo Fisher Scientific NFKBIZ Monoclonal Antibody (OTI1E8), TrueMAB
NFKBIZ 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot과 유세포분석에 적합. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol buffer에 보관. 인간 시료 반응성, 연구용 한정.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E8 |
| Immunogen | Full length human recombinant protein of human NFKBIZ produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.58 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
I-kappa-B-zeta (also known as MAIL and INAP) is an ankyrin-repeat-containing nuclear protein highly homologous to the IkappaB family member Bcl-3. Transcription of IkappaB-zeta is upregulated by stimulation with TLR ligands, IL-1, and IL-6 in cultured B-lymphocytes and monocytes/macrophages, but only faintly in T-lymphocytes, fibroblasts, and endothelial cells. IkappaB-zeta preferentially associates with the NF-kappaB subunit p50 rather than p65, and recombinant IkappaB-zeta proteins inhibit the DNA binding of the p65/p50 heterodimer and the p50/p50 homodimer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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