Thermo Fisher Scientific CD4 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1296)
인간 CD4 단백질을 인식하는 알파카 유래 재조합 단일클론 항체. Flow cytometry, ELISA, SPR 등 다양한 분석에 사용 가능. CHO 세포 발현, 1 mg/mL 농도, Metal-chelate chromatography 정제. 연구용으로만 사용.
- 카탈로그번호
- MA554499
- 판매단위
- pk
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Surface Plasmon Resonance (SPR)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1296 |
| Immunogen | Recombinant Human CD4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes (T helper cells), but may also be expressed by monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression can be detected in thymus, lymph nodes, tonsils, spleen, and in specific regions of the brain, gut, and other non-lymphoid tissues.
CD4 functions to initiate or augment early T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also mediate neuronal damage in infectious or immune-mediated diseases of the central nervous system.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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