Thermo Fisher Scientific MKL2 Polyclonal Antibody
Human 및 Mouse에서 반응하는 Rabbit Polyclonal Anti-MKL2 항체로 Western blot과 ELISA에 적합. Recombinant MKL2(aa 170-300)로 면역생성. Affinity Chromatography로 정제된 액상 항체이며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 170–300 of human MKL2 (NP_0547673) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.07 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805280 |
Product Specific Information
- Immunogen sequence:
IIGVGKEDYP HTQGDFSFDE DSSDALSPDQ PASQESQGSA ASPSEPKVSE SPSPVTTNTP AQFASVSPTV PEFLKTPPTA DQPPPRPAAP VLPTNTVSSA KPGPALVKQS HPKNPNDKHR SKKCKDPKPR V - Positive Samples: LO2, Jurkat, Mouse pancreas
- Cellular Location: Nucleus
Target Information
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), mediating the transient response of many cellular genes to growth stimulation. SRF regulates several muscle genes in response to growth factors and recruits myogenic factors to activate these genes. It is essential for vertebrate mesoderm formation and cardiovascular development. Myocardin and myocardin-related transcription factors (MRTF-A and MRTF-B) interact with SRF to stimulate its transcriptional activity, with MRTF-B being crucial for skeletal myogenic differentiation.
주의사항
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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