Thermo Fisher Scientific Synip Polyclonal Antibody
Human Synip 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.6 mg/mL 농도의 액상 형태입니다. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Synip. Recombinant protein control fragment (Product #RP-93360). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648141 |
Product Specific Information
Immunogen sequence:
LLPCDSSEAD EMERLKCERD DALKEVNTLK EKLLESDKQR KQLTEELQNV KQEAKAVVEE TRALHSRIHL A
Antigen sequence identity:
- Mouse: 77%
- Rat: 76%
Target Information
STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. It inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by binding to STX4A and preventing the interaction between STX4A and VAMP2. Insulin stimulation disrupts this interaction, leading to increased SLC2A4 levels at the plasma membrane. STXBP4 may also regulate insulin release by pancreatic beta cells upon glucose stimulation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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