Thermo Fisher Scientific SIRP gamma Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human SIRPG(Accession Q9P1W8), corresponding to amino acid residues V331-V381. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SIRP gamma,uniProtId:Q9P1W8-1,ncbiNodeId:9606,antigenRange:331-381,antigenLength:387,antigenImageFileName:PA5-104381_SIRP_gamma_Q9P1W8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-104381_SIRP_gamma_Q9P1W8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2853689

Product Specific Information

Antibody detects endogenous levels of total SIRPG.

Target Information

SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily. SIRP gamma is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. SIRP gamma is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.