Thermo Fisher Scientific CDCA7L Polyclonal Antibody
CDCA7L 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성을 가지며, Protein A로 정제된 액상형 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CDCA7L, amino acids 381–454 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cell division cycle-associated 7-like protein (CDCA7L, also known as RAM2) is a transcription factor involved in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter region. CDCA7L also plays an oncogenic role in mediating the transforming effects of MYC in medulloblastoma cells. It may function downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3, CCND1/cyclin D1, and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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