Thermo Fisher Scientific CCR1 Monoclonal Antibody (8E10G6)
인간 CCR1 단백질을 인식하는 마우스 단일클론 항체. Western blot, Flow cytometry, ELISA에 적합. Protein G로 정제된 액상 형태로 제공되며, PBS와 0.05% sodium azide 함유. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8E10G6 |
| Immunogen | Purified recombinant fragment of human CD191 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787295 |
Product Specific Information
Amino acid sequence of the immunogen is proprietary. This antibody has been tested in indirect ELISA.
Target Information
Chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein–coupled receptors. The chemokine receptor subtypes can be divided into two major groups, CXCR and CCR. CCR1, one of the CCR receptors, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils. It binds macrophage-inflammatory protein (MIP-1α), eotaxin, and other related chemokines. Mice lacking CCR1 show defects in neutrophil trafficking and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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