Thermo Fisher Scientific RhoGAP4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL
• Publications: [References not provided]

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:200–1:500
• Publications: [References not provided]

Product Specifications

Product Specific Information

Immunogen sequence:
EHNGMRGLIP HKYITLPAGT EKQVVGAGLQ TAGESGSSPE GLLASELVHR PEPCTSPEAM GPSGHRRRCL VPASPEQHVE VDKAVAQNMD SVFKELLGKT SVRQGLGPAS TTSP

Antigen sequence identity:

• Mouse: 70%
• Rat: 72%

Target Information

This gene encodes a member of the rhoGAP family of proteins, which regulate small GTP-binding proteins belonging to the RAS superfamily.
The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules.
The rat protein stimulates the activity of some Rho GTPases in vitro.
Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus.
Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.