Thermo Fisher Scientific BAIAP2 Polyclonal Antibody
BAIAP2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 인간, 마우스, 랫트에 반응합니다. 항원 친화 크로마토그래피로 정제되었고, PBS 버퍼(40% 글리세롤, 0.02% 아지드) 내 액상 형태로 제공됩니다.
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- PA582976
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- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BAIAP2. Recombinant protein control fragment (Product # RP-93437) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790132 |
Product Specific Information
Immunogen sequence:
AYHSKGKELL AQKLPLWQQA CADPSKIPER AVQLMQQVAS NGATLPSALS ASKSNLVISD PIPGAKPLPV PPELAPFVGR MSAQE
Target Information
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane-bound G-proteins to cytoplasmic effector proteins. It functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, involved in the formation of stress fibers and cytokinesis. This protein participates in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. It has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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