Thermo Fisher Scientific HTR2C Polyclonal Antibody
HTR2C 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상 항체로, PBS/glycerol buffer에 보존. 연구용 전용 시약.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HTR2C (Accession P28335), corresponding to amino acid residues K170–F220 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903339 |
Product Specific Information
This antibody detects endogenous levels of total 5HT2C Receptor.
Target Information
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that binds to several receptor subtypes, including the 5-HT2 family of G-protein-coupled receptors. The HTR2C gene encodes the 2C subtype of serotonin receptor, which undergoes multiple RNA editing events. These edits can alter amino acids within the second intracellular loop, generating receptor isoforms with different G-protein interactions and phospholipase signaling activity, thereby modulating serotonergic neurotransmission in the central nervous system. Abnormalities in 5-HT2C RNA editing have been reported in depressed suicide victims.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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