Thermo Fisher Scientific JAM2 Polyclonal Antibody
JAM2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Human, Mouse, Rat에 반응합니다. Western blot과 ELISA에 적합하며, 액상 형태로 제공됩니다. 세포 접합부 및 막 단백질 연구에 활용됩니다.
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Thermo Fisher Scientific JAM2 Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:500–1:1,000
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 29–238 of human JAM2 (NP_067042.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914823 |
Product Specific Information
- Positive test controls: NIH/3T3, SH-SY5Y, Rat brain, Rat heart
- Localization: Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction
Immunogen sequence:
FSAPKDQQVV TAVEYQEAIL ACKTPKKTVS SRLEWKKLGR SVSFVYYQQT LQGDFKNRAE MIDFNIRIKN VTRSDAGKYR CEVSAPSEQG QNLEEDTVTL EVLVAPAVPS CEVPSSALSG TVVELRCQDK EGNPAPEYTW FKDGIRLLEN PRLGSQSTNS SYTMNTKTGT LQFNTVSKLD TGEYSCEARN SVGYRRCPGK RMQVDDLNIS
Target Information
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.
The JAM2 protein is localized in tight junctions between high endothelial cells, acting as an adhesive ligand for various immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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