Thermo Fisher Scientific PMCA3 ATPase Polyclonal Antibody
PMCA3 ATPase 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응. Western blot 및 IHC(Paraffin) 분석에 적합. 항원 친화 크로마토그래피로 정제된 1 mg/mL 액상 시약. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific PMCA3 ATPase Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 560–887 of Human ATP2B3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548410 |
Product Specific Information
- Recommended positive control: U87-MG
- Predicted reactivity: Mouse (99%), Rat (99%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against large concentration gradients and play a critical role in intracellular calcium homeostasis.
The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes, and their diversity is increased by alternative splicing. Expression of different isoforms and splice variants is regulated in a developmental, tissue-, and cell type-specific manner, suggesting functional adaptation to physiological needs. This gene encodes the plasma membrane calcium ATPase isoform 3.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-30936_PMCA3_ATPase_Q16720-1_Rabbit.svg, PA5-30936_PMCA3_ATPase_Q16720-1_Rabbit_PDP.jpeg)
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