Thermo Fisher Scientific TRAF3IP2 Monoclonal Antibody (4A3)
TRAF3IP2 단백질을 인식하는 Mouse monoclonal 항체로 NF-kappaB 신호 조절 연구에 적합. WB, IHC, ICC, ELISA 등 다양한 응용 가능. Human 반응성, 고순도 Affinity chromatography 정제. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4A3 |
| Immunogen | TRAF3IP2 (AAH02823, 451–565 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LRDKTVMIIV AISPKYKQDV EGAESQLDED EHGLHTKYIH RMMQIEFIKQ GSMNFRFIPV LFPNAKKEHV PTWLQNTHVY SWPKNKKNIL LRLLREEEYV APPRGPLPTL QVVPL
Target Information
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals, and stress.
This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase.
Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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