Thermo Fisher Scientific CYP1A2 Monoclonal Antibody (OTI8F1), TrueMAB
CYP1A2 단백질을 인식하는 Mouse 모노클로날 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. 인간 시료 반응성. 고순도 친화 크로마토그래피 정제. 안정한 액상 형태로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F1 |
| Immunogen | Full length human recombinant protein of human CYP1A2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.77 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), including those found in cigarette smoke.
Although the enzyme’s endogenous substrate is unknown, it can metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates include caffeine, aflatoxin B1, and acetaminophen.
The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3′ untranslated region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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