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Thermo Fisher Scientific SF1 Monoclonal Antibody (OTI7H9)
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SF1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간 시료 반응성이 있으며, 마우스 IgG1 아이소타입의 비결합 액상 항체입니다. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
- 카탈로그번호
- MA527159
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 04. 오후 08:11
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Thermo Fisher Scientific MA527159 SF1 Monoclonal Antibody (OTI7H9) 100 ul pk판매 단위 pk ·
재고 확인 필요
775,200원VAT 포함 852,720원
Thermo Fisher Scientific · Thermo Fisher Scientific SF1 Monoclonal Antibody (OTI7H9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–276 of SF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725336 |
Target Information
Splicing factor 1 (SF1) is a nuclear pre-mRNA splicing factor that specifically recognizes the intron branch point sequence at the 3′ splice site, in conjunction with the large subunit of U2 auxiliary factor (U2AF). It is required for early spliceosome assembly and plays roles in nuclear pre-mRNA retention and transcriptional repression.
SF1 contains:
- N-terminal U2AF ligand motif
- Central hnRNP K homology motif and quaking 2 region (binds branch-site adenosine)
- Zinc knuckles domain
- C-terminal proline-rich domain
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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