Thermo Fisher Scientific FZD10 Polyclonal Antibody
Rabbit polyclonal antibody targeting human FZD10 protein. Validated for IHC (Paraffin) with 6–16 µg/mL dilution. High specificity and cross-species reactivity. Supplied as liquid form, 1 mg/mL, stored at 4°C or -20°C. For research use only.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution
- 6–16 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 14 amino acid peptide from N-terminal extracellular domain of human FZD10 / Frizzled 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550931 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Monkey: 100%
- Gibbon, Hamster, Panda, Dog: 93%
- Marmoset, Mouse, Bovine, Horse, Pig: 86%
Target Information
FZD10 (Frizzled-10) is a 581 amino acid protein belonging to the G-protein coupled receptor Fz/Smo family. It contains a signal peptide, a cysteine-rich domain in the N-terminal region, seven transmembrane domains, and a C-terminal PDZ domain-binding motif. FZD10 is involved in signal transduction and intercellular transmission of polarity information during tissue morphogenesis. It acts as a receptor for Wnt proteins.
Expression is high in placenta, fetal kidney, fetal lung, brain cerebellum, cerebral cortex, medulla, and spinal cord, with very low levels in total brain, frontal lobe, temporal lobe, putamen, adult brain, heart, lung, and skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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