Thermo Fisher Scientific FGD1 Polyclonal Antibody
FGD1 단백질에 특이적인 Thermo Fisher Scientific의 폴리클로날 항체로 인간 시료에 반응합니다. Western blot에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액 형태로 제공되며 연구용으로 사용됩니다.
- 카탈로그번호
- PA551482
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FGD1. Recombinant protein control fragment (Product #RP-91933). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641597 |
Product Specific Information
Immunogen sequence:
DSDPGASEPG LLARRGSGSA LGGPLDPQFV GPSDTSLGAA PGHRVLPCGP SPQHHRALRF SYHLEGSQPR PGLHQGNRIL VKSLSLDPGQ SLEPHPEGPQ RLRSDP
Antigen sequence identity:
- Mouse: 92%
- Rat: 31%
Target Information
FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It binds specifically to the Rho family GTPase Cdc42Hs and stimulates GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also activates the mitogen-activated protein kinase cascade, leading to c-Jun kinase SAPK/JNK1 activation. FGD1 plays an essential role in embryonic development, and mutations in the FGD1 gene result in Aarskog-Scott syndrome.
Note: For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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