
Thermo Fisher Scientific NGF Receptor (extracellular) Polyclonal Antibody
Rabbit polyclonal antibody recognizing extracellular domain of human NGF receptor (p75NTR). Suitable for WB, IHC, ICC/IF, Flow, IP, and IM. Lyophilized form, reconstitutable in DDW. Ideal for studying neuronal differentiation and neurotrophic signaling.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
| Immunomicroscopy (IM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acid residues 188–203 of human p75NTR (Extracellular, stalk domain) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2857275 |
Product Specific Information
- Reconstitute antibody with 50 µL of double distilled water (DDW).
- Store reconstituted solution at 4°C for up to 1 week.
- For long-term storage, aliquot and freeze at -20°C.
- Avoid multiple freeze-thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Peptide sequence: CEEIPGRWIT RSTPPE
Homology: Mouse - identical; Rat - 15/16 amino acids identical.
Target Information
Neurotrophic factors regulate neuronal survival, differentiation, and maintenance in both peripheral and central nervous systems. NGF is essential for sympathetic neuron survival during target competition. Antibodies specific to NGFR p75 are valuable tools for detecting and characterizing NGFR p75, aiding research in neuronal development, plasticity, and repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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