Thermo Fisher Scientific TIMM17A Polyclonal Antibody
TIMM17A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며, Protein A 정제 및 -20°C 보관 조건을 권장합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human TIMM17A (amino acids 31–80) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Translocation of nuclear-encoded preproteins into the mitochondrial matrix requires the coordinated action of the translocases Tom and Tim, located in the outer and inner mitochondrial membranes, respectively. The Tom complex includes multiple receptor and structural subunits facilitating preprotein import. The TIM channel, composed of Tim17, Tim23, and Tim44, mediates the translocation of nuclear-encoded mitochondrial preproteins. Tim17 exists as two isoforms, Tim17a and Tim17b, which differ at their C-termini and are ubiquitously expressed in fetal and adult tissues. Tim17 and Tim23 form the structural components of the inner membrane channel, while Tim44 recruits matrix Hsp70 to assist in preprotein import.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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