Thermo Fisher Scientific RTEL1 Polyclonal Antibody
RTEL1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 최적화되어 있습니다. 인간 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS 버퍼(2% sucrose, 0.09% sodium azide) 내 액상 형태로 제공됩니다.
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Applications
- Western Blot (WB): Tested at 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human RTEL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2690764 |
Target Information
ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair, and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis-dependent strand annealing (SDSA) as well as disassembly of D-loop recombination intermediates. Also disassembles T-loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, ensuring telomere dynamics and stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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