Thermo Fisher Scientific Cdc42EP2 Polyclonal Antibody
Cdc42EP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간 시료 반응성, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 4°C 또는 -20°C 보관.
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- PA558441
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Cdc42EP2. Recombinant protein control fragment (Product #RP-97382) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639564 |
Product Specific Information
Immunogen sequence:
PRLHLETPQP SPQEGGSVDI WRIPETGSPN SGLTPESGAE EPFLSNASSL LSLHVDLGPS ILDDVLQIMD QDLDSMQI
Highest antigen sequence identity to the following orthologs:
- Mouse: 74%
- Rat: 76%
Target Information
Cdc42, a small GTPase, regulates actin polymerization, elongation of cell shape, and cell signaling through interactions with various effector proteins containing a CRIB domain.
Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein localized in both cytoplasm and cytoskeleton. It is highly expressed in heart, and present at lower levels in liver and pancreas.
Cdc42EP2 interacts with Cdc42 and is involved in actin cytoskeleton organization and may influence filament assembly and cell shape.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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