Thermo Fisher Scientific NMD3 Polyclonal Antibody
NMD3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 인체, 마우스, 랫트 시료에 반응하며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태이며, PBS 버퍼와 글리세롤로 안정화되어 있습니다.
- 카탈로그번호
- PA5100291
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NMD3 (Accession Q96D46), corresponding to amino acid residues L385–D435 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2849805 |
Product Specific Information
Antibody detects endogenous levels of total NMD3.
Target Information
NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S ribosomal subunit but is not itself a ribosomal protein.
A mutation in NMD3 can be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover.
Although the NMD3 protein sequence lacks recognizable motifs of known function, its orthologues contain an amino-terminal domain with four repeats of Cx2C, resembling zinc-binding proteins involved in nucleic acid binding or protein oligomerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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