Thermo Fisher Scientific MRPS12 Polyclonal Antibody
Human MRPS12 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 검증 완료. Antigen affinity chromatography로 정제되어 높은 특이성과 재현성을 제공. PBS/glycerol buffer로 안정적이며, 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPS12. Recombinant protein control fragment (Product #RP-100659) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-Specific |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644175 |
Product Specific Information
Immunogen sequence:
MSWSGLLHGL NTSLTCGPAL VPRLWATCSM ATLNQMHRL
Ortholog identity:
- Mouse: 74%
- Rat: 79%
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are involved in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, unlike prokaryotic ribosomes that contain a 5S rRNA.
This gene encodes a 28S subunit protein belonging to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and regulates decoding fidelity and susceptibility to aminoglycoside antibiotics. The mitochondrial seryl-tRNA synthetase gene is located upstream and adjacent to this gene, and both are candidate genes for autosomal dominant deafness (DFNA4). Splice variants differing in the 5′ UTR have been found; all variants encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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