Thermo Fisher Scientific Coenzyme NAD Recombinant Rabbit Monoclonal Antibody (4A4R8)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1 µg/mL

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Peptide Array (Array)

1:500-1:1,000

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Product Specifications

Species Reactivity

Chemical

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

4A4R8

Immunogen

NAD

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Target Information

Coenzyme NAD, also known as nicotinamide adenine dinucleotide, is a crucial molecule involved in various cellular processes. It functions as a cofactor in redox reactions, playing a key role in energy metabolism and cellular respiration. NAD exists in two forms: NAD+ (oxidized) and NADH (reduced). NAD+ accepts electrons during catabolic reactions, such as glycolysis and the citric acid cycle, while NADH donates electrons during anabolic reactions, such as fatty acid synthesis. Additionally, NAD+ is a substrate for enzymes involved in DNA repair, signaling, and gene expression regulation. The balance between NAD+ and NADH is essential for maintaining cellular homeostasis, and disruptions in NAD metabolism have been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.