Thermo Fisher Scientific Aldolase A Polyclonal Antibody
Rabbit polyclonal antibody specific to Human Aldolase A. Validated for WB, IHC(P), and ICC/IF applications. Supplied as a liquid at 1 mg/mL concentration. Suitable for glycolysis-related protein studies and cancer research. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 – 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 – 1:200 |
| Immunocytochemistry (ICC/IF) | 1:50 – 1:200 |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of Human Aldolase A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4 °C for short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803154 |
Target Information
Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose‑1,6‑bisphosphate to glyceraldehyde 3‑phosphate and dihydroxyacetone phosphate.
Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder accompanied by hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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