
Thermo Fisher Scientific Aldolase A Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
1:50-1:200
Immunocytochemistry (ICC/IF)
1:50-1:200
Product Specifications
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide, corresponding to the N-terminus of Human Aldolase A.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2803154
Target Information
Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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