Thermo Fisher Scientific SFTPD Recombinant Rabbit Monoclonal Antibody (001)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Rhesus SFTPD/SP-D/SFTP4.

Target Information

Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and has a structure consisting of multiple globular “head” regions linked by triple-helical, collagen-like strands.
This group includes SP-A, mannan-binding protein, conglutinin, and collectin-43, which bind to the C1q receptor found on various cells. SP-D and SP-A enhance oxygen radical production by alveolar macrophages.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.