Thermo Fisher Scientific PHF15 Polyclonal Antibody
Human PHF15 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 액상 형태, 항원 친화 크로마토그래피로 정제됨. 4°C 단기 보관, 장기 보관 시 -20°C 권장. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PHF15. Recombinant protein control fragment (Product #RP-93570) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645483 |
Product Specific Information
Immunogen sequence:
ASVAADSDVQ VLGPAASPKP LGRLRPPRES KVTRRLPGAR PDAGMGPPSA VAERPKVSLH FDTETDGYFS DGEMSDSDVE AEDGGVQRGP REAGAEEVVR MGVLA
Antigen sequence identity (orthologs):
- Mouse: 80%
- Rat: 78%
Target Information
Scaffold subunit of some HBO1 complexes, which have histone H4 acetyltransferase activity (PubMed:16387653).
Acts as an E3 ubiquitin-protein ligase mediating ubiquitination and proteasomal degradation of histone demethylase KDM1A (PubMed:25018020).
Also acts as a ubiquitin ligase E3 toward itself.
Positive regulator of neurogenesis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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