Thermo Fisher Scientific SPINK6 Monoclonal Antibody (3C10)
SPINK6 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(3C10). Western blot 및 ELISA에 적합하며, 인간 시료에 반응. 액상 형태로 제공되며, PBS(pH 7.4) 버퍼에 보존제 없이 포함. -20°C에서 보관, 동결/해동 반복은 피해야 함.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C10 |
| Immunogen | SPINK6 (AAH32003.1, 1–80 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MKLSGMFLLL SLALFCFLTG VFSQGGQVDC GEFQDTKVYC TRESNPHCGS DGQTYGNKCA FCKAIVKSGG KISLKHPGKCTarget Information
SPINK6 (serine peptidase inhibitor, Kazal type 6), also known as BUSI2, is an 80 amino acid secreted protein containing one Kazal-like domain. It functions as a serine protease inhibitor.
The SPINK6 gene is located on human chromosome 5, which spans approximately 181 million base pairs and represents about 6% of the human genome.
Chromosome 5 is associated with several genetic disorders:
- Cockayne syndrome (ERCC8 gene)
- Familial adenomatous polyposis (APC tumor suppressor gene)
- Treacher Collins syndrome (TCOF1 gene)
- Cri du chat syndrome (deletion of p arm of chromosome 5)
- Therapy-related acute myelogenous leukemia and myelodysplastic syndrome (deletion of q arm or entire chromosome 5)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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