Thermo Fisher Scientific CHRM2 Polyclonal Antibody
CHRM2 단백질을 인식하는 염소 폴리클로날 항체로, Mouse 시료에 반응합니다. Western blot에 최적화되어 있으며, 고순도 및 안정적인 액상 형태로 제공됩니다. 아세틸콜린 수용체 연구 및 신경계 질환 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-QNGDEKQNIVARK (aa 352–364) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933567 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Muscarinic cholinergic receptor 2 (CHRM2) is an acetylcholine receptor that functions as a presynaptic autoreceptor inhibiting acetylcholine release.
The M2 receptor is also suggested to mediate smooth muscle contractility.
In Alzheimer’s disease, selective loss of M2 subtype receptors occurs in cortical and hippocampal regions.
Increased M2 receptor heterozygosity has been associated with depression in women.
The M2 receptor is expressed in various brain regions including the cerebellum, cerebral cortex, hippocampus, medulla, striatum, and thalamus, as well as in lung and prostate tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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