Thermo Fisher Scientific KLF8 Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence:
  PALFNDIKIEP PEELLASDFS LPQVEPVDLS FHKPKAPLQP ASMLQAPIRP PKPQSSPQ
• Highest antigen sequence identity to orthologs: mouse 90%, rat 90%

Target Information

This gene encodes a protein that is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is involved in the regulation of epithelial to mesenchymal transition, which occurs during development and metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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