Thermo Fisher Scientific IARS2 Polyclonal Antibody
Thermo Fisher Scientific의 IARS2 Polyclonal Antibody는 인간 Isoleucyl-tRNA synthetase를 표적으로 하는 토끼 유래 다클론 항체입니다. Western blot과 면역침전(IP)에 적합하며, 1mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution / Usage |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 20 µL/mg of lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 962 to 1012 of human Isoleucyl-tRNA synthetase, mitochondrial |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is hormone-independent, while complex formation with TR occurs in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting phosphorylation may be important for its nuclear translocation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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