Thermo Fisher Scientific SLC26A3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1.0 µg/mL

-

Immunohistochemistry (IHC)

1:600

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-Dependent

-

Immunohistochemistry (Frozen) (IHC (F))

-

View 1 publication 1 publication

Surface plasmon resonance (SPR)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide directed towards the middle region of human SLC26A3

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2688605

Product Specific Information

This target displays homology in the following species: Cow: 100%; Dog: 79%; Guinea Pig: 79%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 86%; Rat: 93%; Sheep: 100%

Target Information

SLC26A3 is a chloride/bicarbonate exchanger that is involved in absorption inside the colon. SLC26A3 helps mediate electrolyte and fluid absorption. The protein encoded by the SLC26A3 gene is a transmembrane glycoprotein that functions as a sulfate transporter, and it is localized to the mucosa. The chloride ions transported by SLC26A3 cross the cell membrane in exchange for biocarbonate ions. SLC26A3 is localized in the mucosa of the lower intestinal tract, specifically the apical membrane of the columnar epithelium and in some goblet cells. Diseases associated with SLC26A3 protein dysfunction include congenital chloride diarrhea and congenital secretory chloride diarrhea 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.