Thermo Fisher Scientific RSPO3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RSPO3. Recombinant protein control fragment (Product #RP-94892). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RSPO3,uniProtId:Q9BXY4-1,ncbiNodeId:9606,antigenRange:192-269,antigenLength:272,antigenImageFileName:PA5-56307_RSPO3_Q9BXY4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56307_RSPO3_Q9BXY4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646848

Product Specific Information

Immunogen sequence: PTNETRKCTV QRKKCQKGER GKKGRERKRK KPNKGESKEA IPDSKSLESS KEIPEQRENK QQQKKRKVQD KQKSVSVS

Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 67%.

Target Information

RSPO3 is a member of the R-spondin family and plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. RSPO3 has been shown to be involved in regulating the balance between angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis and may be involved in tumor development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.