Thermo Fisher Scientific NEUROG3/Neurogenin 3/NGN3 (Transcription Factor) Monoclonal Antibody (PCRP-NEUROG3-1E10)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Flow Cytometry (Flow)

1-2 µg/10^6 cells

-

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

1-2 µg/100-500 µg total protein

-

Peptide Array (Array)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

PCRP-NEUROG3-1E10

Immunogen

Recombinant human full-lengthNEUROG3protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NeuroG3,uniProtId:Q9Y4Z2-1,ncbiNodeId:9606,antigenRange:1-214,antigenLength:214,antigenImageFileName:50674-MSM3-P1ABX_NeuroG3_Q9Y4Z2-1_House_mouse.svg,antigenImageFileNamePDP:50674-MSM3-P1ABX_NeuroG3_Q9Y4Z2-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Target Information

Neurog 3 protein contains one basic helix-loop-helix (bHLH) domain.It is both necessary and sufficient to induce endocrine islet cell differentiation from embryonic pancreatic progenitors. Not only does itinitiates endocrine cell differentiation, italso promotes islet cell maturation and maintains islet function. It is reported that Neurogenin 3 can redirect the differentiation of bipotential secretory progenitors to endocrine rather than goblet cell fate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.