Thermo Fisher Scientific MCM9 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MCM9. Recombinant protein control fragment (Product #RP-94959). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MCM9,uniProtId:Q9NXL9-1,ncbiNodeId:9606,antigenRange:1073-1136,antigenLength:1143,antigenImageFileName:PA5-56653_MCM9_Q9NXL9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56653_MCM9_Q9NXL9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643814

Product Specific Information

Immunogen sequence: SPPPERKNRG ERGPSSPPTT TAPMRVSKRK SFQLRGSTEK LIVSKESLFT LPELGDEAFD CDWD

Highest antigen sequence identity to the following orthologs: Mouse - 47%, Rat - 53%.

Target Information

Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8- MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.