Thermo Fisher Scientific SLC19A1 Polyclonal Antibody
Rabbit polyclonal antibody against human SLC19A1. Validated for IHC(P) and ICC/IF applications. High specificity and affinity purified. Supplied in liquid form with glycerol for stability. Suitable for research use only.
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- PA555190
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SLC19A1. Recombinant protein control fragment (Product # RP-91233) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647371 |
Product Specific Information
Immunogen sequence:
AQALSVQDKG LGGLQPAQSP PLSPEDSLGA VGPASLEQRQ SDPYLAQAPA PQAAEFLSPV TTPSPCTLCS AQASGPEAAD ETCPQLAVHP PGVSKLGLQC LPSDGVQNV
Highest antigen sequence identity to orthologs:
- Mouse: 28%
- Rat: 27%
Target Information
Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these two mechanisms has been proposed to facilitate folate uptake in certain cell types. Methotrexate (MTX), an antifolate chemotherapeutic agent, is actively transported by the carrier-mediated uptake system. RFC1 plays a critical role in maintaining intracellular folate concentrations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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