Thermo Fisher Scientific OR4B1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:3,000

-

Immunohistochemistry (IHC)

1:300-1:3,000

-

Miscellaneous PubMed (Misc)

-

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide as a part of human olfactory receptor (OR4B1, OST208, OR11-106) conjugated to an immunogenic carrier protein was used as the immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: Olfactory receptor OR4B1.

Target Information

Olfactory receptors are G protein-coupled receptor proteins that localize to the cilia of olfactory sensory neurons where they display affinity for and bind to a variety of odor molecules. The genes encoding olfactory receptors comprise the largest family in the human genome. The binding of olfactory receptor proteins to odor molecules triggers a signal transduction cascade that leads to the production of cAMP via an olfactory-enriched adenylate cyclase. This event ultimately leads to transmission of action potentials to the brain and the subsequent perception of smell. OR4B1 (Olfactory receptor 4B1), also known as Olfactory receptor OR11-106, is a 309 amino acid multi-pass membrane protein that functions as an odorant receptor, effectively binding odor molecules and initiating the propagation of signals to the primary olfactory cortex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.