Thermo Fisher Scientific PLOD2 Monoclonal Antibody (OTI8A4), TrueMAB
인간 PLOD2 단백질을 인식하는 단클론 항체로, Western blot에 최적화되어 있습니다. 마우스 IgG2a 아이소타입이며, 비결합형 액상 형태로 제공됩니다. 1 mg/mL 농도, 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 359–640 of human PLOD2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a membrane-bound homodimeric enzyme localized to the cisternae of the rough endoplasmic reticulum. This enzyme, requiring iron and ascorbate as cofactors, catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups serve as attachment sites for carbohydrates in collagen, contributing to the stability of intermolecular crosslinks. Deficiencies in lysyl hydroxylase activity are associated with Ehlers-Danlos syndrome type VIB, and mutations in this gene are linked to Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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