Thermo Fisher Scientific WDR39 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human WDR39. Recombinant protein control fragment (Product #RP-91642). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:WDR39,uniProtId:O76071-1,ncbiNodeId:9606,antigenRange:212-335,antigenLength:339,antigenImageFileName:PA5-53654_WDR39_O76071-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53654_WDR39_O76071-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649576

Product Specific Information

Immunogen sequence: CSDDRTVRIW RQYLPGNEQG VACSGSDPSW KCICTLSGFH SRTIYDIAWC QLTGALATAC GDDAIRVFQE DPNSDPQQPT FSLTAHLHQA HSQDVNCVAW NPKEPGLLAS CSDDGEVAFW KYQR

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.

Target Information

WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.