Thermo Fisher Scientific Cathepsin L Polyclonal Antibody
Cathepsin L 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot에 적합하며, 고순도(>95%) 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in Human CTSL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803596 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The Cathepsin L protein is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen, elastin, and alpha-1 protease inhibitor, a key regulator of neutrophil elastase activity. This enzyme is implicated in pathological processes such as myofibril necrosis in myopathies, myocardial ischemia, and renal tubular response to proteinuria. It belongs to the peptidase C1 family and is a disulfide-linked dimer composed of heavy and light chains derived from a single precursor. Multiple transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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