Thermo Fisher Scientific MPZL1 Polyclonal Antibody
Thermo Fisher Scientific의 MPZL1 Polyclonal Antibody는 인간 MPZL1 단백질을 인식하는 토끼 IgG 기반 항체로, 면역조직화학(IHC) 등에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MPZL1. Recombinant protein control fragment (Product #RP-91056) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644093 |
Product Specific Information
Immunogen sequence:
KEIFVANGTQ GKLTCKFKST STTGGLTSVS WSFQPEGADT TVSFFHYSQG QVYLGNYPPF KDRISWAGDL DKKDASINIE NMQFIHNGTY ICDVKNPPDI VVQPGHIRLY VVEKENLPVF PVWVV
Highest antigen sequence identity to the following orthologs:
- Mouse: 81%
- Rat: 81%
Target Information
Cell surface receptor involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Acts as a major receptor for concanavalin-A (ConA) and participates in ConA-induced cellular signaling, likely involving Src family tyrosine-protein kinases. Isoform 3 appears to have a dominant negative role, blocking tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 or isoform 3, may regulate integrin-mediated cell motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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