Thermo Fisher Scientific Perilipin A+B Polyclonal Antibody
Perilipin A와 B 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합합니다. Human 및 Mouse 시료에 반응하며, Protein A 정제 및 고농도(1 mg/mL) 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1:50 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Perilipin A+B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adipose tissue functions as an energy reserve and is tightly regulated. Adipocytes secrete various physiologically important proteins including lipoprotein lipase (LPL), leptin, adipocyte complement-related protein of 30 kDa (Acrp30), resistin, and perilipin.
Perilipin is an intracellular lipid droplet-associated protein that is hormonally regulated and localized on the lipid droplet surface. Upon lipolytic stimulation, perilipin is phosphorylated by protein kinase A, which modulates hormone-sensitive lipase (HSL) activity to control triacylglycerol hydrolysis.
Perilipin expression is restricted to adipocytes and steroidogenic cells, and two isoforms, Perilipin A and B, are known to result from alternative splicing of a single gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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